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Acute toxicity data from rodent models puts the LD50 well above concentration ranges used in published research protocols
Increased inflammation : NAD+ plays a role in regulating inflammatory responses
A 2016 study in Cellular and Molecular Gastroenterology and Hepatology showed that KPV dramatically reduced colonic tumorigenesis in a model of colitis-associated cancer an effect that was abolished in PepT1-knockout animals
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